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http://hdl.handle.net/123456789/49
Title: | Nickel and Oxidative Stress: Cell Signaling Mechanisms and Protective Role of Vitamin C |
Authors: | Das, Swastika Reddy, R. Chandramouli Chadchan, Kailash S. Patil, Arun J. Biradar, M.S. Das, Kusal K. |
Keywords: | Antioxidant, cyclooxygenase, hypoxia-inducible factor-1α, nickel, oxidative stress, tumor necrosis factor-α. |
Issue Date: | 2020 |
Publisher: | Bentham Science |
Series/Report no.: | 1871-5303; |
Abstract: | Background: Nickel activates the signaling pathways through the oxygen sensing mechanism and the signaling cascades that control hypoxia-inducible transcriptional gene expressions through oxidative stress. This review emphasizes on the recent updates of nickel toxicities on oxidant and antioxidant balance, molecular interaction of nickel and its signal transduction through low oxygen microenvironment in the in-vivo physiological system. |
URI: | http://hdl.handle.net/123456789/49 |
Appears in Collections: | F P |
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File | Description | Size | Format | |
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Das-MS.EMIDDT.pdf | 472.39 kB | Adobe PDF | View/Open |
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