Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/49
Title: Nickel and Oxidative Stress: Cell Signaling Mechanisms and Protective Role of Vitamin C
Authors: Das, Swastika
Reddy, R. Chandramouli
Chadchan, Kailash S.
Patil, Arun J.
Biradar, M.S.
Das, Kusal K.
Keywords: Antioxidant, cyclooxygenase, hypoxia-inducible factor-1α, nickel, oxidative stress, tumor necrosis factor-α.
Issue Date: 2020
Publisher: Bentham Science
Series/Report no.: 1871-5303;
Abstract: Background: Nickel activates the signaling pathways through the oxygen sensing mechanism and the signaling cascades that control hypoxia-inducible transcriptional gene expressions through oxidative stress. This review emphasizes on the recent updates of nickel toxicities on oxidant and antioxidant balance, molecular interaction of nickel and its signal transduction through low oxygen microenvironment in the in-vivo physiological system.
URI: http://hdl.handle.net/123456789/49
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